As for Vyvanse, I’ve tried it but found that it became less effective much faster than adderall. Is it possible that the contradictory information regarding the effect of pH on Vyvanse has to do with the distinction of gastric pH vs blood pH? And I love it but hate it. This could be a great mystery solver for me! I take Vyvanse. That sure sounds like something you can at least try eliminating first before increasing your dose. Perhaps there is one that would interfere less with the stimulants? One of the side effects of the Adderall going FULL BLAST is that I’m lonely. 🙂. The most definitive information can be found on the product label. It came on STRONG. I lost my job four months ago and dropped out of life. Mostly, the public has no idea. Earlier today I took a rather large dose of Concerta, about 90 mg, followed by a small dose of valerian root a few hours later and 2 rolaids because I began to feel some heartburn and had an upset stomach. 🙂. Hello and thanks for the article, it really set some important thoughts in motion – but unfortunately, this whole case seems so MASSIVEly complicated on so many levels, just from trying, testing, searching and reading. This might include: The general rule, I’d heard: Do not consume citric acid an hour before or after taking the stimulant. The basic mechanism of Zantac suggests that the acid-lowering result might affect methylphenidate absorption. It’s not as easy as you may think. I do not find this as a common adverse effect of these meds, so I guess I’m special! I don’t need a higher dose (at least not now), I googled what I thought it was but only found one hit (didn’t look too hard but still…), I had not eaten anything for about five hours, I was hungry but I didn’t want to eat too much because I thought I would go to sleep (Lol right now it’s 220am and I’m WIDE AWAKE). and right now nothing is working and life sucks! Baby steps. _____, P.S. And without that test, I would keep chasing my tail without a clue. There are so many possibilities. Thanks for bringing my attention to not replying to Patricia. The ups and downs have been overwhelming at times. I’m really sorry about that. Obviously, I was not going to risk losing access to my medication altogether by being viewed as a “drug seeker”…which is the last thing I am…but it drives me nuts that she is SO rigid with her decisions. I take 60 mg of mixed amphetamine salts every day. I do almost nothing in the way of “self-advertising.” I give more of my time, freely, than any other ADHD expert around. I am plant based, I eat tons of veggies and clean foods, and I am in great shape. Problem is, I am afraid to mess with my Adderall because I can’t do my job without it. You might have a different experience.”, “It took a while to get used to but I weigh about 160 lb. You’re taking another medication? But I have zero side affects. 🙂. Above all, try not to judge if the medication is working by how it “feels” but by how it affects your functioning. I’m afraid no one can tell you with absolute accuracy what exactly will happen when you take the suggested doses of these two medications. If possible, I’d encourage you to investigate steps you can take that might reduce/eliminate the need for the PPI. Even for normal metabolizers. I read a lot of articles on ADD and can not seem to find what to eat hat won’t class with the medication. lower absorption of amphetamines. I’m still living at home with my parents. Thanks for your comment and the kind words. 57% of those users who reviewed Concerta reported a positive effect, while 17% reported a negative effect. Ammonium chloride is used to spice up dark sweets called salty licorice (very popular in Nordic countries, especially in Finland), in baking to give cookies a very crisp texture, and in the vodka Salmiakki Koskenkorva for flavouring. We develop antibodies to the foods we eat most often. It’s a bit of a minefield…, Hi Vicki…absolutely, the complexity of our physiology is pretty much off the charts. Because when avoiding acidic foods, this might go against what’s good for gut health, and another thing will be adhering to one’s own IgG-index. Sometimes that happens when a person with ADHD starts stimulants; they are finally able to relax and the body wants sleep. When it comes to medical care, people with ADHD are the clients — not beggars! Who knows? The same side effects more mild initially, then around noon I would crash and for the rest of the day into the night the head ache and sheer discomfort became overwhelming. I sincerely appreciate the work you do to help give us a voice. For many people, it’s several hours shorter. As far as the drug itself it's great! I love how I feel when I take Ritalin but the first dose usually gives me diarrhea, wears off after 4hrs, gives me the shakes and I often forget to take my 2nd or 3rd dose. In other words, grapefruit juice can be a problem in two big ways: 1. This is also an unregulated product, so you’ll never know how much exactly you’re getting or what else might be in it. Focus on: eating a healthy diet with plenty of fresh leafy greens and vegetables I am 36 years old and was officially diagnosed with ADHD about a year ago, but had come to realize the possibility a couple years before that. I think I'm a non-responder. If I take one of these for two consecutive months it becomes apparant that the formulation is different, and often times it means the medication is ineffective. Starting you on 50 mg Vyvanse was grossly irresponsible. I would not risk it. Less caffeine or soda? (7.2) One of these acidifying agents is ammonium chloride, also known as, Urinary acidifying agents may reduce blood levels of amphetamine. I’m speaking only of men with ADHD, which is associated with mood dysregulation and poor inhibition. https://www.vyvanse.com/coupon-adult-adhd, And yes, Mydayis might be worth a trial but, like you, I know few people who have tried it and have only mixed reports from them. I feel numb, I can’t pay attention, it’s almost like there is nothing in my head. What about if you cannot tell between your compulsive symptoms and those of a more impulsive nature? I’m not surprised, though. 4. What if you were prescribed eyeglasses but told you can wear them only 3-4 hours a day? until absorption began and variable delays in the time until the first peak concentration, the time until And Netflix ‘s Take Your Pills – SUCKS and should not be taken as the truth I had to watch it in secret (not with kids around) as my 8 year old was diagnosed this year and takes concerta and I smelled the documentary’s ignorant agenda from the title – it lumps real adhd patients in with recreational stimulant abusers and college performance enhancer abusers and suggests that ALL just take the pills as unfair advantage and everyone’s overmedicated and adhd is over diagnosed over treated. I truly appreciate all you help! This phenomenon has created problems for many people over the years — and continuing. https://www.healthline.com/health/lysine-foods#lysine-in-vegetables. His appetite has actually increased! It’s a pity that people who blindly do & get away with the most stuff are the best off, and the most ethical of us have the worst financial ability. We don’t quite know why, but one reason might be that there is an extra mechanism of action. Adderall could be causing your acid reflex. For example: Great article. Adderall is tricky because in some people it can provide a feeling of “super human focus” and so these people might not work on implementing other strategies, such as getting sufficient sleep, eating well, using a calendar/planner, etc. Concerta is a very good medication for those with ADHD/ADHD-I.”, “I’ve been on Concerta for the past week and a half. The only thing I do with my mailing list is notify readers of a new post. He agreed. How is Cotempla XR-ODT different to other brands of methylphenidate? I went back to my doctor and she said she did not want to up the dosage, and gave me Concerta 36 MG. 30mg of Adderall XR. Mix that with comorbidity in OCD (that appears to be OCD or stems from ADHD), and it’s just a mess trying to balance it out. administered (see DOSAGE AND ADMINISTRATION). Concerta, Ritalin, etc.). I can’t quite remember the specifics (I’m sure I have the study around here somewhere…but it goes without saying that my organizational skills are somewhat lacking!) There’s a lot to “unpack” in your comment. Ah! Way back when my husband was finally diagnosed (thanks to my figuring it out), I thought…great…now I can leave the treatment to the MD and my molecular biologist husband — or, as I came to call them later, “Dumb and Dumber!”. So try to get some sleep. During the next two weeks, when progesterone levels rise, this can counter estrogen. What I’m saying is I can’t imagine someone taking even a regular dose of this without tums. But the cautions don’t stop with Ph. I was studying to be a scientist before realizing the corruption in the industry, and how all the other runts are studying this and then following commands intentionally made to ruin the world, made me stop, and I can tell you the interesting thing about amphetamine is that it increases s845 glua1 production while methamphetamine which is propagandized as mainly a drug of abuse reduces it. depression, anxiety, etc. amphetamine molecule, thereby increasing urinary excretion. Not all food intolerances have to be permanent, I’ve seen. So from your research, would you expect antacids to have a negative impact on Ritalin effectiveness in an adult? One minute you say your doctors have failed you. Many (not all) people who did well on Adderall do better on Vyvanse. But one thing I have noticed recently is that my usually very regular menstrual cycle has started to become irregular. Thanks. Is there a protein, or anything, that could be “not binding” properly on something else in my brain and therefore, making all stimulants useless? I'm happy, calm, still bit anxious but I'm better everyday. I hope I’ll have better luck with this. A few years back, my doctor suggested to try taking the 36mg ones, but for me this didn't work because I felt kinda lost and foggy. Honestly -people wrote a book about how they are “the only god’s only family”, but if you say that isn’t true, YOU get called a fascist. We literally noticed a difference in him the very first day. I recently read a book by Jonathan Aviv called The Acid Watcher Book. For those it doesn’t work on, it can have different effects, including the opposite effect of stimulants in a somewhat unique way. I tried Ritalin 3 times a day at 10 mg each and then did decently but sure enough I was tired constantly. I am not “judging your lifestyle.” I am going simply on the facts you provide. I am so sorry to have forgotten to attempt answering your question. (ammonium chloride, sodium acid phosphate, etc.) [144] Due to the effect pH has on absorption, amphetamine also interacts with gastric acid reducers such as proton pump inhibitors and H2 antihistamines, which increase gastrointestinal pH (i.e., make it less acidic).[144]. User Reviews for Concerta to treat ADHD. So do stimulants or SSRI’s help impulsiveness? My son was on VyVance 30mg for three years and I absolutely loved what it did for him, on the days it worked. Most people don’t realize that few patients actually die of cancer. Also, starting “low and titrating slow” is less of a shock to the system. I have mentioned to my DR. several times that I think the acid in my stomach could be affecting it, but I cannot tell her it’s not working because she may stop prescribing it, and she tells me she cannot go any higher in dosage, which I don’t think would help anyway. ADHD is hardest for me because I’m a very unique metabolized that is very fast at metabolizing stimulants. Then it got away from me. There’s only so much you can do with MDs who compensate for their inexpertise by being overly rigid. Perhaps that protein powder has amino acids that don’t compete with each other? It’s their number and severity, in the presence of impairment, that makes the diagnosis. And nothing. And if he hasn’t, maybe someone could write and ask him to. OH! I don’t know if this is 100 percent scientifically accurate account of what happens because I’ve read people get prescribed methylphenidate class stims And Amph-based ones at the same time (in which case they should take the amph ones first /methylphenidate ones second to account for the action on dopamine) and I’m sure people will be correcting me after this post – but my personal experience (before knowing about this action on dopamine from wellbutrin/bupropion) is that this is true – my Dex was blunted severely and noticeably the very first time I took wellbutrin so I stopped it. We have to depress the entire system (tricyclic antidepressants, AEDs) which then diminishes overall functionality. That’s because, I presume, the stimulant is helping them to “focus” on sleep and relax — and pay off sleep debts. In fact, some people prefer the generics to the brand. Alot of doctors aren’t well versed in it, prescribe medications that target the acid in the stomach which actually do little to nothing for LPR, hence no change in your symptoms. I’d offer only one observation about the food intolerances/sensitivities: We might sometimes have it a bit backward. But it might be worth your experimenting. cautiously with vasopressor agents. Thanks for this post, it’s nice to see some intelligent conversation about these medications by people who need them to live saner, more productive lives! Completely cancelled it out. 7. Some are better than others, and some pharmacies have been horribly maximizing profit over efficacy. His sleep has not been affected..He actually goes to bed now the first time we tell him to. I’ve had acid reflux on and off for a few years. — and take a daily multi-vitamin/mineral for good measure. 🙂, ADHD meds jack up stress hormones to help focus. What if you were prescribed eyeglasses but told you can wear them only 3-4 hours a day? I take 20mg XR in the morning with breakfast, and take 10mg IR one to twice a day (depending on how long I work). Many pwADHD do not get good sleep! Recently due to state requirements my Dr requested a urine test as to ensure I was taking my meds as prescribed. For some people with ADHD, untreated ADHD neurobiology itself might contribute to food intolerances and sensitivities. The wrong medications caused a lot of damage in my personal life. So, even if you are eating a sufficient or even “massive” amount of amino acids, that doesn’t mean your physiological will uptake them. PLease keep us posted! Have you tried that? But if you are also drinking coffee, that could be contributing as well. Hardly left the house. Any time I take anything with zinc in it, I throw up immediately. I had genesight genetic profile testing done and none of the advise I got from any doctor has helped and I’m tired of being cold and tired like I’m a lifeless zombie. I know many young people with ADHD who fell for the larger-than-life temptations of Adderall+ It didn’t end well. ADHD brain patterns mean that all kinds of messages are slow to travel or get “corrupted in transmission.” So, what about the signals that initiate hormone production, release, etc.? I don’t really believe I’m perhaps truly OCD, but I have a lot of suspicion it’s adhd with the overactive amygdala and overactive limbic system. I read on one site that concerta could interact with certain anti-acids but haven’t been able to find this information elsewhere. I’ve been taking adderall for 12 years. For example, citric acid and antacids can mean the difference between a stimulant working—or not. Just faster than the claims. A year ago was when I got officially diagnosed and treated medicinally. I checked the label insert for various stimulants. I’ve often wondered if that is a big problem for children in the U.S., for whom such a breakfast is almost ubiquitous. Best of luck in these medical adventures. This post is in response to many emails and questions I’ve been getting about how to treat Attention Deficit/Hyperactivity Disorder (ADHD) or Attention Deficit Disorder (ADD) with nootropics.. 2000 mg Tyrosine X 2 I suggest a single tablet because it’s very unlikely to affect your PH to the point where it will hurt absorption, whereas acidity is a far bigger no no. However, the tests were negative for the drug, but I experienced the effects of the medication. He didn’t even notice. It appears that Ritalin/methylphenidate might not reliably show up on the average drug test. Can you find a physician who knows how to test for hormonal levels and uses bio-identical hormones? You are not off-topic. I have severe insomnia and I get irritated really easily. And I was eating fruit every day for lunch. Or maybe it’s too high a dose? In some cases, the proteins you consume contain amino acids that compete for receptors. A lot of people think that antacids increase amphetamine absorption. lol). This would only be detrimental to organs such as the spleen and kidney which are not the intended targets of the drug, and especially are affected by changes in bloodflow (with levoamphetamine causing the most bloodflow impairment of mainstream ADHD drug constituents). If i take a multivitamin with 200% vitamin c (as ascorbic acid) at bedtime will it affect my 9am dose of adderall? Every new med I would try would work the same way. But try not to over-do it, either. I forgot to ask my doctor about this when he prescribed it today and pharmacist don’t seem to be very helpful here. That does not happen anymore. Side effects: Fast heart beat, LOTS of energy and maybe a libido boost. Problem is, as many people know, it’s tough to switch docs…there is usually a long wait time and I don’t know of any in particular, in my area, who might be a better fit. It’s a shot to the ego, but look up adrenal fatigue and many places list adhd meds as contributors to adrenal fatigue. lowering acid that results in reduced Concerta effectiveness). Any given drug can have strange effects on the body. So was jumping from 36 mg Concerta to 54 mg Concerta, after you were already experiencing significant side effects. But from my perspective (observing this field over 20 years and how it can snag people with ADHD, especially when overlying on naturopaths and others who are not qualified to understand neurogenic factors such as ADHD), IgG tests are definitely oversold and mostly misinterpreted. Results were consitantly negative. 🙂. Overall, I think it's helped me a lot in focusing on course work and it's intended purpose.”, “I've been on this medication for about 14 YEARS now. With children, think gummy bears, “fruit” chews, and all the other candy masquerading as fruit items. But some time ago I had an ear infection and had to take antibiotic that work bad with protein pump inhibitors. Such as Vyvanse. Is there an equivalent for methl the way Vyvanse is a precursor to dextro? It might be that treating the anxiety as well as the ADHD would be a more helpful strategy. So I think now I will ask her to try Concerta to see if that will work for me, because as of now, my ADHD is really affecting my job performance and my everyday life. I was on ritalin/methylphenidate last winter, and it mostly gave me anxiety (esp. Do you think generic adderol works as well as “real” adderol? ”, Thank you for this. So now I’m taking Zantac, a h2 blocker, have been for 4 years but I need something stronger. I tend to get one of two types, the round orange pills or the round white ones that crumble easy. Everyone is different. Hi, They are only descriptors of what the behavior “looks like” or maybe “feels like.”. Begging your pardon, but I am not a forum or a commercial website peddling quackery. I wonder if your physician has done thorough thyroid testing. It sounds like they affect you the way Adderall affects some people — like attaching a booster rocket to one’s behind. I wish that this was the first time I’d read such an account, of how RECKLESS physicians have made life worse for people with ADHD instead of better. I wish you much luck. But I noticed that in the afternoon, I would have trouble again with counting and focusing. The appetite suppressant does help me out since I'm working on weight loss, but it can also be a struggle to eat at times or find a food that is appetizing in general because of it. In other words, these people also tend to do less well on the brand. https://adhdrollercoaster.org/tools-and-strategies/chapter-14-denial-and-neurobiology/. He’s a bachelor in his sixties, the family’s well-established “eccentric.” He has little patience for social niceties, yet is emotionally hurt very easily. I’m never going back to Counseling because I’ve done it for 6 years and tried 5 therapists and not helpful for me. Because the stimulant helped to regulate gastric function. I’ve never heard of Mydayis before, and I’m glad to see that more options are coming to market. As for your docs’ dire prediction, I would take them with a grain of salt. I take Vyvanse to combat the sedation and appetite effects of migraine drugs. I have been taking multi-vitamins much more regularly because I know I don’t always get key nutrients in my diet. It can be SO difficult to balance all these extremes. Life got better. These include a higher protein diet less sugar and carbs and also taking probiotics and magnesium and vitamin B supplements. I could find no evidence of FD&C # dyes in Concerta, though perhaps different names are being used. I am simply concurring that your currently reported mental/physical state is unsurprising, given 40 mg Dexedrine, caffeine, and Wellbutrin, not to mention Testosterone. It does seem that stimulants can sometime adversely affect the immune system, and I don’t quite understand it. Here you can find all you need for your creative DIY projects from fabrics, sewing patterns and yarn to … My understanding is that when estrogen levels are higher (typically during the first two weeks of a period), that promotes the release of serotonin and dopamine molecules. I’ve heard from many women with fibromyalgia, too, who have found the ADHD diagnosis and treatment definitely diminished their pain and lethargy. For tics, you might want to investigate taking a B complex vitamin and magnesium citrate. Many people with ADHD will experience an uptick in anxiety from a stimulant, perhaps especially the amphetamines. Yes, I realize that many people who are abusing stimulants fancy themselves “hacking” the potency with acid, alkaline, etc. But yes, please conduct your experiment and share an update! If only our bodies came with individualized operating manuals! Now I do. Because of it I've been able to wean off my antidepressant and no longer have to take it. Perhaps it is improving the immune system through less stress. Yep, taking Rx for ADHD is not the “easy fix” so many people criticize it as being. To add further confusion, I didn’t have any memorable, serious complications like this earlier in Spring, or Winter. 2. You might want to keep a log, to see if the acid reflux and nausea are not so random. That’s above my pay grade. Thanks also for providing a first-hand report on Mydayis. Very enlightening and gives me hope! Is it possible there is a mood disorder? All it says is that antacids which can themselves turn into acids (amphoteric ones) reduced completely undesirable digestive side effects of amphetamine. It’s slow in coming. SO…now that you know a whole bunch about me lol…I’m wondering if you think any of these things could be affecting the absorption of my Adderall? After doing my own research, I found out that citric acid, and fruits interact with Adderall XR, basically stopping it from working. Granted, the demands on my time are pretty extreme — I am about a year out from finishing my PhD in clinical psychology, which has been a long haul with ADHD, to say the least. Hi. That’s interesting. Downward dose adjustment of these drugs may be required Read on. If it were me, I would not rely on the prescribing physician being able to advise. https://www.cosmopolitan.com/uk/body/health/a19752273/pcos-side-effects-mental-health-issues-depression-anxiety/. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Behavior mod is a very effective tool for ADHD as well in many patients. Maybe someone with authority in that area can opine. But, my money is on the acid-reducing effect of the proton-pump inhibitor. Thanks for your reply — I haven’t come across too many people who are also aware, as you are, of the unique experience women may have with stimulants due to hormone fluctuations. https://www.medicalnewstoday.com/articles/324229, So yes, I urged not obsessing yet still trying to do all the things in that list. I’m not qualified to advise you on your diet. Generics are notorious for using colorants, binders, fillers, etc. He is more loving and affectionate now whereas before he was always so defiant. We reluctantly gave him this drug and it has saved my marriage and our overall quality of life has improved drastically. Hi, I was diagnosed with ADHD about 7 yrs ago, took Adderall for a few months then stopped, I didn’t see it making any difference. If I take the antacid at a different time than the adderall will that help the adderall to work better? 2. The big variable with neurotransmitter precursors from proteins is primarily uptake. Kind of like how I need the Vyvanse to tolerate the headache meds, but too much Vyvanse causes headaches :/. I have lost weight even though I eat the same. I take adderall every morning and I do my best to avoid acidic items like flavored waters ans colas etc. My understanding is that different foods can affect different parts of the gut. Acidifying agents:  I am a 50 year old Male with multiple medical issues including liver and kidney transplant and all associated medications. Paper inserts don’t say much about interactions, not on foods. I don’t like that, either. For several months, I felt like SUPERMAN!! But all meds have cons.”, “I have been taking this for 4 months now. You can email me if it’s easier. But I am soooooo grateful for this post. I tried a few other drugs with various but minimal effects and then just stopped the drugs altogether. Concerta has an average rating of 6.9 out of 10 from a total of 332 ratings for the treatment of ADHD. I found that the therapeutic effects of the adderall are decreased, but the toxic effects, like nausea and headache, are increased when i take the antacids with it. Now I’m taking them back and feel calm. But perhaps there are other factors, such as poor or insufficient sleep, insufficient water consumption, and even the varying generic of the medication. I was taking ritilin and had urine tests to show I was taking it. I qualify for Mensa based on a test, I can’t hold a job. When Ritalin LA was administered with a high fat breakfast to adults, Ritalin LA had a longer lag time I see only websites trying to make a buck peddling claptrap. I found an old thread (@2009) on this topic (http://www.addforums.com/forums/showthread.php?t=68046), with my comment: It’s so annoying. How do these guys get out of med school? But money. Vitamins and minerals are also used to metabolize medications. A couple of questions. I don’t know about interactions with blood sugar. Adderall tends to do that (peter out after a while). I have never been told anything about antacids! Without it, you can’t tell where’s a good place to be and what you should be doing and whether you should do what you just did another time in the future-this is also known as memory. I have increased anxiety, hallucinations, paranoia, and mood swings from this drug. Hi I take 54mg of xenidate (concerta) and my doctor just prescribed me 150mg ranitidine twice a day. Without them I feel a better sense of control, yet I cannot seem to get my mind going without stimulants, but equally the stimulants I take make my mind move so fast I can’t really put the brakes on. Regards, Thomas. That touches upon another factor: Getting a sufficient variety of amino acids. Because Wellbutrin has a complex mechanism of action (we don’t quite understand it, even today), that means there can be a whole range of complex side effects. – Thomas. Then hour two comes and it’s time to take my next dose. This med works, just be cautious if you’re bipolar.”. I hope you can find a physician who knows how to treat complex issues. We comply with the HONcode standard for trustworthy health information -. Perhaps this leads to depletion. “He started calling me at nine or ten at night, asking me for cookies. For people with ADHD, it’s often a balancing act between the stimulants and an antidepressant. It might be clearing your system very quickly.